A young Nigerian-American financier struggles with love, family, and a prescription drug dependency as his ambitions steer him down a criminal path.

Don Champagne seems to have it all: a successful business, a perfect house, perfect kids and a perfect wife. Unfortunately, when his wife, Mona (Katherine Heigl), learns of Don's affair with a pretty new salesgirl (Jordana Brewster), this suburban slice of heaven spirals out of control. Don soon realizes that Mona will stop at nothing, including murder, to maintain their storybook life where "perception is everything".

Bert and Arnie's Guide to Friendship follows the romantic misadventures of Bert Sheering, a sophisticated, yet sexually repressed author and Arnie Hubert, an executive and unabashed ladies man. When Bert discovers that Arnie is sleeping with his wife, this modern day odd couple are launched into a journey filled with comedy, romance and ultimately, friendship.

Bebe and DeeDee, best friends with different relationship problems, embark on a New York City misadventure with their new acquaintance, Clementine.